IJIMT 2013 Vol.4(2): 265-268 ISSN: 2010-0248
DOI: 10.7763/IJIMT.2013.V4.403

The Development of Innovative Herbal Extract Oral Film for the Unpleasant Mouth Odour

C. Jittinan, S. Krisana and V. Pakpachong
Abstract— The development of innovative herbal extract encapsulated in quick-dissolving films for the unpleasant mouth odor derived from the encapsulated Mangosteen extract nanoparticles incorporated into pullulan-alginate films and using solvent casting as film formation. The oral blend films were prepared from a mixture of pullulan and alginate. Encapsulated mangosteen extract nanoparticles (15 and 20% w/w), mint oil (0.2%, w/w) and glycerol (10%, w/w) were incorporated in the films to act as natural antimicrobial agent and plasticizer, respectively. The oral blend films exhibited antibacterial activity against S.mutan, S.sanguinis and P.gingivalis by using by macro broth dilution assay. Percent encapsulated mangosteen extract on antibacterial activity was investigated. The increasing in growth inhibition (%) was found when percent encapsulated mangosteen extract was increased. When 15% and 20% encapsulated mangosteen extract content its was shown that growth inhibition of more than 99 % were found for all (S.mutan S.sanguinis and P.gingivalis). Acceptance of innovative products and films suspended mouth odor herbal extract from a sample 50 found that overall satisfaction with the product. Prototype than product innovation in existing products on the market. In terms of convenience in use. Ingredients of products. Effectively suspended mouth odor, Nutrition, Innovation.

Index Terms— Quick-dissolving films, pullulan-alginate, encapsulated mangosteen extract.

S. Krisana is with Metallurgy Materials Science Research Institute, Chulalongkorn University,Thailand (e-mail: krisana.s@chula.ac.th).

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Cite: C. Jittinan, S. Krisana and V. Pakpachong, " The Development of Innovative Herbal Extract Oral Film for the Unpleasant Mouth Odour," International Journal of Innovation, Management and Technology vol. 4, no. 2, pp. 265-268, 2013.

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